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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCPEP1 All Species: 28.48
Human Site: Y42 Identified Species: 41.78
UniProt: Q9HB40 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB40 NP_067639.1 452 50831 Y42 E G K E V W D Y V T V R K D A
Chimpanzee Pan troglodytes XP_001172174 452 50766 Y42 E G K E V W D Y V M V R K D A
Rhesus Macaque Macaca mulatta XP_001104815 452 50613 Y42 E G K E V W D Y V T V R K D A
Dog Lupus familis XP_537688 477 53125 Y67 E G K E V W D Y V T V R K D A
Cat Felis silvestris
Mouse Mus musculus Q920A5 452 50948 Y42 E G K E V W D Y V T V R K D A
Rat Rattus norvegicus Q920A6 452 51156 Y42 E G K E V W D Y V T V R E D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521733 560 62210 Y148 E G K E A W G Y V D V R S N A
Chicken Gallus gallus NP_001012821 446 49959 V32 P R E L W G Y V Q V R S K A H
Frog Xenopus laevis NP_001088737 443 49367 K35 G Y V A V R D K A Y M F W W L
Zebra Danio Brachydanio rerio NP_956486 445 49600 Y35 Q A K E S W G Y V D V R D G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392686 435 48876 V35 G E Q E W G Y V K V R P A S Y
Nematode Worm Caenorhab. elegans NP_872130 445 50095 D33 G V I Q Y D E D W G Y V D I R
Sea Urchin Strong. purpuratus XP_785691 470 52220 W40 H K E P K Q D W G Y V G V R P
Poplar Tree Populus trichocarpa XP_002313552 489 53783 V47 G S E E W G Y V E V R P R A H
Maize Zea mays NP_001148149 464 50034 V41 E E W G Y V E V R P K A H M F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67Y83 461 51734 V41 E A W G Y V E V R P K A H M F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96 82.8 N.A. 82 82.7 N.A. 60.7 65.9 65.9 62.8 N.A. N.A. 42 41.8 47.8
Protein Similarity: 100 99.3 99.1 88.2 N.A. 90.7 91.8 N.A. 70.7 78.9 77.2 77.6 N.A. N.A. 59.2 58.6 63.6
P-Site Identity: 100 93.3 100 100 N.A. 100 93.3 N.A. 66.6 6.6 13.3 53.3 N.A. N.A. 6.6 0 13.3
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 73.3 13.3 20 60 N.A. N.A. 13.3 13.3 26.6
Percent
Protein Identity: 42.7 45 N.A. 42.9 N.A. N.A.
Protein Similarity: 57.2 58.6 N.A. 60.7 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 13.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 7 7 0 0 0 7 0 0 13 7 13 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 50 7 0 13 0 0 13 38 0 % D
% Glu: 57 13 19 63 0 0 19 0 7 0 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 13 % F
% Gly: 25 44 0 13 0 19 13 0 7 7 0 7 0 7 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 13 0 13 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % I
% Lys: 0 7 50 0 7 0 0 7 7 0 13 0 38 0 0 % K
% Leu: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 7 7 0 0 13 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % N
% Pro: 7 0 0 7 0 0 0 0 0 13 0 13 0 0 7 % P
% Gln: 7 0 7 7 0 7 0 0 7 0 0 0 0 0 0 % Q
% Arg: 0 7 0 0 0 7 0 0 13 0 19 50 7 7 7 % R
% Ser: 0 7 0 0 7 0 0 0 0 0 0 7 7 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 32 0 0 0 0 0 % T
% Val: 0 7 7 0 44 13 0 32 50 19 57 7 7 0 0 % V
% Trp: 0 0 13 0 19 50 0 7 7 0 0 0 7 7 0 % W
% Tyr: 0 7 0 0 19 0 19 50 0 13 7 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _